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Class 12 Biology — Chapter 4: Principles of Inheritance and Variation

92 practice questions · 31 Easy · 31 Medium · 30 Hard

Practise Class 12 Biology Chapter 4, "Principles of Inheritance and Variation", with 92 NCERT-aligned multiple-choice questions. The set is split into 31 Easy, 31 Medium and 30 Hard questions, so you can warm up on the fundamentals and then push into the exam-level problems that separate top scorers in CBSE Board exams and NEET UG.

"Principles of Inheritance and Variation" is one of the chapters where diagram-based recall, terminology and NCERT line-by-line accuracy really pays off. Each MCQ on this chapter is timed and uses exam-grade marking (+2 correct, −1 wrong, 0 skipped), training the same accuracy-under-pressure that real papers demand. Every question carries a short explanation, so a wrong answer becomes a quick lesson rather than a dead end — the fastest way to close gaps before a test.

Use this chapter as targeted revision: attempt the Easy set first to confirm your basics on Principles of Inheritance and Variation, then move to Medium and Hard to test application and problem-solving. Your accuracy, streaks and XP save automatically, and the chapter feeds into your overall Class 12 Biology mastery score. A few sample questions are shown below; sign in free to practise all 92.

Key concepts: Principles of Inheritance and Variation (Class 12 Biology)

This chapter covers Mendel's laws of inheritance, deviations like incomplete dominance and epistasis, chromosomal theory, linkage, sex determination and genetic disorders.

Mendel's laws
Law of dominance, law of segregation (factors separate in gametes) and law of independent assortment.
Monohybrid & dihybrid ratios
A monohybrid cross gives a 3:1 phenotypic ratio; a dihybrid cross gives 9:3:3:1.
Deviations from Mendel
Incomplete dominance (1:2:1 phenotype), co-dominance (e.g. AB blood group), and multiple alleles.
Linkage & sex determination
Linked genes are inherited together; sex is determined by XX/XY (humans) or XX/XO systems.
Genetic disorders
Mendelian (haemophilia, sickle-cell anaemia, colour blindness) and chromosomal (Down's, Turner's, Klinefelter's syndromes).

Key formulas — Principles of Inheritance and Variation

Monohybrid ratio
phenotypic 3 : 1 (genotypic 1 : 2 : 1)
Dihybrid ratio
phenotypic 9 : 3 : 3 : 1

💡 Exam tips for Principles of Inheritance and Variation

  • Incomplete dominance changes the phenotypic ratio to 1:2:1 (same as the genotypic ratio).
  • Haemophilia and colour blindness are X-linked recessive — more common in males.

Sample questions

Q1Easy

The father of modern genetics is:

A.Charles Darwin
B.Gregor Mendel✓ correct
C.Watson and Crick
D.Thomas Morgan
Why

Gregor Mendel formulated the laws of inheritance using pea plant experiments.

Q2Medium

In a monohybrid cross between two heterozygotes (Tt × Tt), the F₂ phenotypic ratio is:

A.1 : 1
B.3 : 1✓ correct
C.9 : 3 : 3 : 1
D.1 : 2 : 1
Why

Tt × Tt → 1 TT : 2 Tt : 1 tt. Phenotype ratio = 3 dominant : 1 recessive.

Q3Hard

Mendel's law of segregation is based on which cellular event?

A.Mitosis
B.Crossing over
C.Separation of homologous chromosomes during meiosis I✓ correct
D.Random fertilisation alone
Why

Allele pairs separate when homologous chromosomes separate in anaphase I of meiosis.

Principles of Inheritance and Variation — FAQs

What are the key concepts in Class 12 Biology Principles of Inheritance and Variation?+

This chapter covers Mendel's laws of inheritance, deviations like incomplete dominance and epistasis, chromosomal theory, linkage, sex determination and genetic disorders. Key ideas include Mendel's laws, Monohybrid & dihybrid ratios, Deviations from Mendel, Linkage & sex determination, Genetic disorders.

What does Class 12 Biology Chapter 4 (Principles of Inheritance and Variation) cover on XamBaaz?+

It covers 92 NCERT-aligned MCQs on "Principles of Inheritance and Variation" — 31 Easy, 31 Medium and 30 Hard — each with a timed quiz and an instant explanation, suitable for CBSE Board exams and NEET UG.

Are these "Principles of Inheritance and Variation" questions free to practise?+

Yes — sign in with Google to practise "Principles of Inheritance and Variation" free. Full unlimited access is ₹999/year (limited-time launch price), with no per-chapter charges.

How should I revise "Principles of Inheritance and Variation" for the exam?+

Start with the Easy quiz to confirm your fundamentals, then attempt Medium and Hard for application-level practice. Review each explanation, retry the questions you miss, and track your accuracy on this chapter until it is consistently high.

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