Human Reproduction — Class 12 MCQs with Answers
Class 12 CBSE Biology · Chapter 2
90 practice questions · 30 Easy · 30 Medium · 30 Hard · Updated
Practise the most important Class 12 CBSE Biology questions from Chapter 2, "Human Reproduction". You get 9 timed quizzes made from 90 NCERT-based MCQs, with answers and explanations. The questions are split into 30 Easy, 30 Medium and 30 Hard. Warm up on the basics, then move on to the exam-level questions that set top scorers in CBSE & Maharashtra HSC Board exams, MHT-CET and NEET UG apart.
To score well in "Human Reproduction", focus on diagrams, key terms and knowing NCERT line by line. Each MCQ here is timed and uses exam-style marking (+4 correct, −1 wrong, 0 skipped). This trains you to stay accurate under time pressure, as real papers need. Every question has a short explanation, so a wrong answer becomes a quick lesson. It is the fastest way to fix gaps before a test.
Use this chapter for focused revision. Start with the Easy set to check your basics on Human Reproduction, then move to Medium and Hard to practise applying them. Your accuracy, streaks and XP save automatically. This chapter also adds to your overall Class 12 Biology mastery score. 14 sample questions are solved in full below, with the answer and a worked explanation. Sign in free to start practising.
Key concepts: Human Reproduction (Class 12 Biology)
Human reproduction: the male and female reproductive systems, spermatogenesis and oogenesis, the hormone-driven menstrual cycle, fertilisation in the fallopian tube, cleavage to blastocyst and implantation, the placenta as an endocrine organ, and parturition and lactation.
- Seminiferous tubules
- Site of sperm formation in the testis; Sertoli cells nourish spermatids and secrete inhibin, while Leydig (interstitial) cells make testosterone.
- Spermatogenesis
- Formation of sperm from diploid spermatogonia via meiosis; one primary spermatocyte yields four sperms. Spermiogenesis reshapes spermatids into motile sperm.
- Oogenesis
- Formation of the ovum; begins in the foetus, arrests at prophase I, and one oogonium gives one ovum plus polar bodies (meiosis II ends at fertilisation).
- Graafian follicle
- The mature ovarian follicle that ruptures at ovulation to release the secondary oocyte; its remnant becomes the corpus luteum.
Human Reproduction — important questions & MCQs with answers (Class 12 Biology)
14 solved questions from this chapter's difficulty levels, each with its answer and explanation. The other 76 are timed and scored when you sign in.
- Q1Easy
Site of sperm production:
A.AdrenalB.ProstateC.LiverD.Testis (seminiferous tubules)✓ CorrectAnswer: D. Testis (seminiferous tubules)
Explanation: Spermatogenesis — production of sperm from diploid spermatogonia — occurs inside the seminiferous tubules of the testis, not the epididymis, which only stores and matures sperm afterward.
- Q2Easy
The onset of the first menstruation at puberty is called:
A.GestationB.MenopauseC.OvulationD.Menarche✓ CorrectAnswer: D. Menarche
Explanation: Menarche is the first menstrual cycle at puberty, marking the start of a female's reproductive phase; menopause, by contrast, marks its end decades later.
- Q3Easy
Site of fertilisation in females:
A.UterusB.Fallopian tube (oviduct)✓ CorrectC.VaginaD.OvaryAnswer: B. Fallopian tube (oviduct)
Explanation: Fertilisation happens in the ampullary region of the fallopian tube (oviduct), where sperm meets the secondary oocyte; the uterus is only the later site of implantation.
- Q4Easy
Permanent stoppage of the menstrual cycle around 45–50 years is termed:
A.Menopause✓ CorrectB.MenarcheC.GestationD.ParturitionAnswer: A. Menopause
Explanation: Menopause is the permanent cessation of menstrual cycles around age 45-50, caused by the ovaries running out of responsive follicles, ending the reproductive phase.
- Q5Easy
Sperms are produced in the human testis inside the:
A.Rete testisB.Vas deferensC.EpididymisD.Seminiferous tubules✓ CorrectAnswer: D. Seminiferous tubules
Explanation: Sperm are produced inside the seminiferous tubules of the testis; the rete testis and epididymis only collect, transport and mature sperm afterward.
- Q6Easy
Release of the secondary oocyte from the ovary is called:
A.MenstruationB.ImplantationC.Ovulation✓ CorrectD.CapacitationAnswer: C. Ovulation
Explanation: Ovulation is the release of the secondary oocyte from the Graafian follicle, triggered by the mid-cycle LH surge around day 14 of a 28-day cycle.
- Q7Medium
The transformation of spermatids into spermatozoa is called:
A.Spermiogenesis✓ CorrectB.SpermiationC.SpermatogenesisD.SpermatocytogenesisAnswer: A. Spermiogenesis
Explanation: Spermiogenesis is the shaping of round spermatids into streamlined, motile spermatozoa; their eventual release into the tubule lumen is the separate step called spermiation.
- Q8Medium
Spermatogenesis is initiated by hormone:
A.FSH (follicle-stimulating hormone)✓ CorrectB.InsulinC.AdrenalineD.ThyroxineAnswer: A. FSH (follicle-stimulating hormone)
Explanation: FSH from the pituitary drives spermatogenesis by acting on Sertoli cells, while LH stimulates Leydig cells for testosterone; together the two gonadotropins regulate sperm production.
- Q9Medium
A primary spermatocyte completes meiosis to produce:
A.One spermB.Two diploid cellsC.Four haploid spermatids✓ CorrectD.Two spermatidsAnswer: C. Four haploid spermatids
Explanation: A primary spermatocyte (2n) undergoes meiosis I to give two secondary spermatocytes, then meiosis II to yield four haploid spermatids — equal division throughout, unlike oogenesis.
- Q10Medium
Average menstrual cycle length:
A.60 daysB.7 daysC.~28 days✓ CorrectD.90 daysAnswer: C. ~28 days
Explanation: The human menstrual cycle averages about 28 days, with ovulation near day 14; individual cycles normally range from roughly 21 to 35 days, not a fixed number.
- Q11Medium
For normal fertility, the sperm count per ejaculation should be at least about:
A.1 million per mLB.60 million per mL with >60% normal and >40% motile✓ CorrectC.100 per mLD.10 per mLAnswer: B. 60 million per mL with >60% normal and >40% motile
Explanation: Normal fertility requires a semen density around 60 million sperm per mL, with over 60% of normal morphology and over 40% actively motile — below this, fertility drops sharply.
- Q12Hard
If a single primary spermatocyte and a single primary oocyte each complete gametogenesis, the total number of functional gametes produced is:
A.8B.5 (4 sperms + 1 ovum)✓ CorrectC.4D.2Answer: B. 5 (4 sperms + 1 ovum)
Explanation: One primary spermatocyte completes meiosis to give four functional sperm, but one primary oocyte's unequal division gives only one functional ovum — five gametes total, not equal numbers.
- Q13Hard
Implantation in humans typically occurs:
A.3 monthsB.Same dayC.30 daysD.~6-7 days after fertilisation✓ CorrectAnswer: D. ~6-7 days after fertilisation
Explanation: The blastocyst reaches the uterus and implants about 6-7 days after fertilisation, not immediately — cleavage and travel through the oviduct take nearly a week.
- Q14Hard
Which match is INCORRECT?
A.Sertoli cells — secrete testosterone✓ CorrectB.Leydig cells — secrete androgensC.Acrosome — enzymes for egg penetrationD.Middle piece — mitochondriaAnswer: A. Sertoli cells — secrete testosterone
Explanation: Testosterone is secreted by Leydig cells, not Sertoli cells — Sertoli cells instead nourish developing germ cells and secrete inhibin, a common mix-up between the two.
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Start this chapter free →Human Reproduction — FAQs
What are the key concepts in Class 12 Biology Human Reproduction?+
Human reproduction: the male and female reproductive systems, spermatogenesis and oogenesis, the hormone-driven menstrual cycle, fertilisation in the fallopian tube, cleavage to blastocyst and implantation, the placenta as an endocrine organ, and parturition and lactation. Key ideas include Seminiferous tubules, Spermatogenesis, Oogenesis, Graafian follicle.
What does Class 12 Biology Chapter 2 (Human Reproduction) cover on XamBaaz?+
It has 90 NCERT-based MCQs on "Human Reproduction": 30 Easy, 30 Medium and 30 Hard. Together they make 9 timed quizzes, and you never get the same set twice. Every question has an instant explanation. They help you prepare for CBSE & Maharashtra HSC Board exams, MHT-CET and NEET UG.
Are these "Human Reproduction" questions free to practise?+
Yes. Sign in with Google to practise "Human Reproduction" free. Full unlimited access is ₹999/year on a launch offer until 1 December 2026. No chapter is charged separately.
How should I revise "Human Reproduction" for the exam?+
Start with the Easy quiz to check your basics, then try Medium and Hard to practise applying them. There are 9 timed quizzes on this chapter, so you can come back for a fresh set instead of one you have seen. Read each explanation, retry the questions you miss, and track your accuracy until it stays high.
Are these "Human Reproduction" MCQs available with answers?+
Yes. 14 sample questions are shown here in full, each with the correct option and a step-by-step "Why" explanation. Sign in free with Google to start practising, with instant scoring.
Is there negative marking in the "Human Reproduction" quizzes?+
Yes. The timed quizzes use exam-style marking: +4 for a right answer, −1 for a wrong one and 0 for a skip, the same negative marking as NEET UG. MHT-CET and CBSE board papers have no negative marking. Our mocks for those are scored their way.
What are the important questions from Human Reproduction (Class 12 Biology)?+
The questions that matter most test Seminiferous tubules, Spermatogenesis, Oogenesis, Graafian follicle. This page shows 14 solved important MCQs with answers and explanations; all 90 questions on the chapter are available as timed quizzes once you sign in.
Is there an online quiz for Human Reproduction?+
Yes — Class 12 Biology Human Reproduction has timed online quizzes at Easy, Medium and Hard levels, with instant scoring and a worked explanation on every question. The first quiz on the chapter is free.